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 Scholar Profile -  Concise Version  Concise Version Information
Name:   Susan Kirkland
Affiliation:  Research Fellow, Centre for Pathology, Imperial College London  (Last Known)
Communities:  Pathology and Laboratory Medicine, Biomedical Science, Clinical Medicine

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"Type I collagen inhibits differentiation and promotes a stem cell-like phenotype in human colorectal carcinoma cells." British journal of cancer 101, No. 2 2009, pp. 320-6.
Kirkland, S C
From Abstract:
indicate that type I collagen promotes expression of a stem cell-like phenotype in human colorectal... the colorectal cancer cell phenotype. The effect of type I collagen on morphology, localisation of cell... of human colorectal carcinoma cell lines. RESULTS: Human colorectal carcinoma cells grown on type I
"Alpha2beta1 integrin regulates lineage commitment in multipotent human colorectal cancer cells." The Journal of biological chemistry 283, No. 41 2008, pp. 27612-9.
Kirkland, Susan C; Ying, Huijun
From Abstract:
The human colorectal epithelium is maintained by multipotent stem cells that give rise... established a human colorectal cancer cell line with multipotent characteristics (HRA-19) and developed... extracellular matrix receptors in multilineage differentiation by these multipotent human colorectal cancer
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